Scientists in Edinburgh and Cologne have identified genes that could explain why some people age faster than others. A balanced iron level in the blood could play an important role. The suggests your "Nature Communications" study published in.
The Team identified ten Gene regions associated with a long-life, long-term health and Reach old age together. In addition, they observed that genes that have to do with the iron budget, were over-represented in these individuals.
They showed by statistical methods that genes involved in iron metabolism in the blood, contribute to a healthy long life. The iron level in the blood is influenced by the diet. Unusually high or very low values are associated with age-related diseases such as Parkinson’s, liver disease and a worse defense against infections.
Dr. Paul Timmers from the Usher Institute at the University of Edinburgh said: "These results speak very much in favour of too high a content of iron reduced in the blood the healthy life. A control of these values could prevent age-related damage. We believe that our results could explain the iron metabolism is also why a very high consumption of iron-rich red meats with age-related diseases such as heart disease has been linked."
The researchers used three indicators for the effects of biological aging: The life span, the number of years of life free from diseases such as dementia, cancer and heart disease (the "Gesundheitsspanne") and an extremely long life span (longevity). In the analysis of genetic data, a fins of 1.75 Million people, about 60,000 of them had reached a very high age.